Oncología Clínica y Traslacional


  • Aparicio LA., Castosa R., Blanco, M., Concha, A., Valladares, M., Calvo, L., and Figueroa, A. Clinical relevance of epithelial cell plasticity in cancer progression. (2015, under review).
  • Antolín, S., Calvo, L., Blanco-Calvo, M., Paz Santiago, M., Lorenzo-Patiño, MJ., Haz-Conde, M., Santamarina I., Figueroa, A., Antón-Aparicio, LM., and Valladares-Ayerbes, M. Circulating miR-200c and miR-141 and outcomes in patients with breast cancer. BMC Cancer (2015, under review).
  • Aparicio, LA.,* Castosa, R.,* Haz, M., Rodriguez, M., Blanco, M., Valladares, M., and Figueroa, A. Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells. BMC Cancer (2013) 14:507.DOI: 10.1186/1471-2407-14-507.
  • Blanco-Calvo, M.*, Tarrío, N.*, Reboredo, M., Haz-Conde, M., García, J., Quindós, M., Figueroa, A., Antón-Aparicio,L., Calvo, L and Valladares-Ayerbes, M. Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer. Future Oncol. (2014) 10(7):1187-202.
  • Aparicio, LA., Abella V., Valladares, M., and Figueroa, A. Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition. Cell Mol Life Sci (2013) 70: 4463-4477.
  • Abella V., Valladares, M., Rodriguez, T., Haz, M., Blanco, M., Tarrío, N., Iglesias, P., Aparicio, LA. and Figueroa, A. miR-203 regulates cell proliferation through its influence on Hakai expression. Plos One (2012) 7: e52568.
  • Valladares-Ayerbes M, Reboredo M, Medina-Villaamil V, Iglesias-Díaz P, Lorenzo-Patiño MJ, Haz M, Santamarina I, Blanco M, Fernández-Tajes J, Quindós M, Carral A, Figueroa A, Antón-Aparicio LM, Calvo L. Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cáncer. J Transl Med (2012) 10: 186.
  • Aparicio LA. Valladares, M., Blanco, M., Alonso, A., Figueroa, A. Biological influence of Hakai in cancer: 10-year review. Can. Met. Rev. (2012) 31: 375-386.
  • Blanco-Calvo, M., Calvo, L., Figueroa, A., Haz-Conde, M., Antón-Aparicio, L. and Valladares-ayerbes, M. Circulating microRNAs: Molecular Microsensors in Gastrointestinal Cáncer. Sensors (2012) 12, 9286-9299.
  • Valladares-Ayerbes, M., Blanco, M., Reboredo, M., Lorenzo-Patiño, MJ., Iglesias-Díaz, P., Haz, M., Díaz-Prado, S., Medina, V., Santamarina, I., Pertega, S., Figueroa, A., Antón-Aparicio, L. Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer. Int J Mol Sci (2012) 13: 4367-4387.
  • Rodriguez-Rigueiro, T., Valladares-Ayerbes, M., Haz-Conde, M., Blanco, M., Aparicio, G., Fernández-Puente, P., Blanco FJ., Lorenzo, MJ., Aparicio, LA and Figueroa A.Novel procedure for protein extraction from formalin-fixed paraffin-embedded tissues. Proteomics (2011) 11: 2555-2559.
  • Aparicio-Gallego, G., Blanco M., Figueroa A., Garcia-Campelo, R., Valladares-Ayerbes M., Grande-Pulido, E. and Antón-Aparicio, L. New Insights into Molecular Mechanisms of Sunitinib-Associated Side Effects. Mol. Cancer Ther. (2011) 10: 2215-2223.
  • Rodríguez-Rigueiro, T., Valladares-Ayerbes, M., Haz-Conde, M., Aparicio LA. and Figueroa, A. Hakai reduces cell-substratum adhesions and increases cell invasion in epithelial cells. BMC Cancer (2011) 11:474.
  • Valladares-Ayerbes , M., Blanco, M. , Haz, M., Medina, M., Iglesias-Díaz, P., Lorenzo-Patiño, MJ., Reboredo, R., Santamarina, I., Figueroa, A., Antón-Aparicio, LM. and Calvo, L. Prognostic impact of disseminated tumor cells and microRNA-17-92 cluster deregulation in gastrointestinal cancer. Int J Oncol (2011) 39: 1253-1264.
  • Valladares-Ayerbes, M., Díaz-Pazo, S., Reboredo, M., Medina, V., Lorenzo-Patiño, MJ., Iglesias-Díaz, P., Haz, M., Santamarina, I., Calvo, MB., Quindós Varela M., Figueroa. A., and Aparicio, LA. Evaluation of Plakophilin-3 mRNA as a Biomarker for Detection of Circulating Tumor Cells in Gastrointestinal Cancer Patients. Cancer Epidemiol. Biomarkers Prev. (2010) 19: 1432-1440.
  • Calvo, MB., Figueroa, A., Grande Pulido E., Garcia Campelo R. and Aparicio LA. Potential role of sugar transporters in cancer and their relationship with anticancer therapy. Int J Endocrinol (2010) 1-14.
  • Aparicio, G., Calvo, MB., Medina, V., Fernández, O., Jiménez, P., Lema, M., Figueroa, M., and Aparicio, LA. Comprehensive lung injury pathology induced by mTOR inhibitors. Clin. Transl. Oncol. (2009) 11:499-510.
  • *Figueroa, A., Fujita, Y., and Gorospe, M. Hacking RNA: Hakai promotes tumorigenesis by enhancing the RNA-binding function of PSF. Cell Cycle (2009) 8: 3648-3651. (*Corresponding author)
  • Figueroa, A., Kotani H., Toda, Y., Mazan-Mamczarz, K., Mueller, EC., Otto, E., Disch, L., Norman, M., Ramdasi, R., Keshtgar, M., Gorospe, M. and Fujita, Y.Novel roles of Hakai in cell proliferation and oncogenesis. Mol. Biol. Cell (2009) 20: 3533-3542.
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