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  • Fernández-García L, Fernandez-Cuenca F, Blasco L, López-Rojas R, Ambroa A, Lopez M, Pascual Á, Bou G, Tomás M. Relationship between tolerance and persistence mechanisms in Acinetobacter baumannii strains with AbkAB Toxin-Antitoxin system. Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.00250-18. doi: 10.1128/AAC.00250-18. [Epub ahead of print] PubMed PMID: 29463538.
  • García-Castillo M, García-Fernández S, Gómez-Gil R, Pitart C, Oviaño M, Gracia-Ahufinger I, Díaz-Regañón J, Tato M, Cantón R; iCREST Study Group. Activity of ceftazidime-avibactam against carbapenemase-producing Enterobacteriaceae from urine specimens obtained during the infection-carbapenem resistance evaluation surveillance trial (iCREST) in Spain. Int J Antimicrob Agents. 2018 Mar;51(3):511-515. doi: 10.1016/j.ijantimicag.2018.01.011. Epub 2018 Jan 31. PubMed PMID: 29371104.
  • Álvarez-Fraga L, Vázquez-Ucha JC, Martínez-Guitián M, Vallejo JA, Bou G, Beceiro A, Poza M. Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii. Virulence. 2018 Jan 1;9(1):496-509. doi: 10.1080/21505594.2017.1420451. PubMed PMID: 29334313.
  • Moscoso M, García P, Cabral MP, Rumbo C, Bou G. A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus. Virulence. 2018 Jan 1;9(1):604-620. doi: 10.1080/21505594.2017.1417723. PubMed PMID: 29297750.
  • M.Lopez; et al.. 2018. Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade (PMID: 29410443) Nature Scientific Report.
  • Fernández-Cuenca F, Tomás M, Caballero-Moyano FJ, Bou G, Pascual Á; Spanish Group of Nosocomial Infections (GEIH); Group of Mechanisms of Action and Resistance to Antimicrobials (GEMARA); Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC); Spanish Network for Research in Infectious Diseases (REIPI). Reporting antimicrobial susceptibilities and resistance phenotypes in Acinetobacter spp: a nationwide proficiency study. J Antimicrob Chemother. 2017 Dec 13. doi: 10.1093/jac/dkx464. [Epub ahead of print] PubMed PMID: 29244131.
  • Oviaño M, Gómara M, Barba MJ, Sparbier K, Pascual Á, Bou G. Quantitative and automated MALDI-TOF MS-based detection of the plasmid-mediated quinolone resistance determinant AAC(6')-Ib-cr in Enterobacteriaceae. J Antimicrob Chemother. 2017 Oct 1;72(10):2952-2954. doi: 10.1093/jac/dkx218. PubMed PMID: 29091187.
  • Palacios-Baena ZR, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale P, Oliver A, Pintado V, Gasch O, Martínez-Martínez L, Pitout J, Akova M, Peña C, Molina Gil-Bermejo J, Hernández A, Venditti M, Prim N, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Giamarellou H, Almela M, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Paño-Pardo JR, Torre-Cisneros J, Souli M, Bonomo RA, Carmeli Y, Paterson DL, Pascual Á, Rodríguez-Baño J; Spanish Network for Research in Infectious Diseases (REIPI)/European Study Group of Bloodstream Infections and Sepsis (ESGBIS)/INCREMENT Group. Empiric Therapy With Carbapenem-Sparing Regimens for Bloodstream Infections due to Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: Results From the INCREMENT Cohort. Clin Infect Dis. 2017 Oct 30;65(10):1615-1623. doi: 10.1093/cid/cix606. PubMed PMID: 29020250.
  • Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A. Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01238-17. doi: 10.1128/AAC.01238-17. Print 2017 Nov. PubMed PMID: 28848013; PubMed Central PMCID: PMC5655067.
  • Vázquez-Ucha JC, Maneiro M, Martínez-Guitián M, Buynak J, Bethel CR, Bonomo RA, Bou G, Poza M, González-Bello C, Beceiro A. Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01172-17. doi: 10.1128/AAC.01172-17. Print 2017 Nov. PubMed PMID: 28807908; PubMed Central PMCID: PMC5655052.
  • Álvarez-Fraga L, Rumbo-Feal S, Pérez A, Gómez MJ, Gayoso C, Vallejo JA, Ohneck EJ, Valle J, Actis LA, Beceiro A, Bou G, Poza M. Global assessment of small RNAs reveals a non-coding transcript involved in biofilm formation and attachment in Acinetobacter baumannii ATCC 17978. PLoS One. 2017 Aug 1;12(8):e0182084. doi: 10.1371/journal.pone.0182084. eCollection 2017. PubMed PMID: 28763494; PubMed Central PMCID: PMC5538643.
  • Otero F, Santiso R, Tamayo M, Bou G, Gosálvez J, Fernández JL. Rapid Detection of Bacterial Susceptibility or Resistance to Quinolones. Methods Mol Biol. 2017;1644:95-104. doi: 10.1007/978-1-4939-7187-9_7. PubMed PMID: 28710755.
  • Pérez-Llarena FJ, Vázquez-Ucha JC, Kerff F, Zamorano L, Miró E, Cabral MP, Fleites A, Lantero M, Martínez-Martínez L, Oliver A, Galleni M, Navarro F, Beceiro A, Bou G. Increased Antimicrobial Resistance in a Novel CMY-54 AmpC-Type Enzyme with a GluLeu(217-218) Insertion in the Ω-Loop. Microb Drug Resist. 2017 Jun 30. doi: 10.1089/mdr.2017.0017. [Epub ahead of print] PubMed PMID: 28665771.
  • Cabral MP, García P, Beceiro A, Rumbo C, Pérez A, Moscoso M, Bou G. Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy. Nat Commun. 2017 May 26;8:15480. doi: 10.1038/ncomms15480. PubMed PMID: 28548079; PubMed Central PMCID: PMC5458566.
  • López M, Blasco L, Gato E, Perez A, Fernández-Garcia L, Martínez-Martinez L, Fernández-Cuenca F, Rodríguez-Baño J, Pascual A, Bou G, Tomás M. Response to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing. Front Cell Infect Microbiol. 2017 May 9;7:143. doi: 10.3389/fcimb.2017.00143. eCollection 2017. PubMed PMID: 28536672; PubMed Central PMCID: PMC5423435.
  • Pérez-Varela M, Corral J, Vallejo JA, Rumbo-Feal S, Bou G, Aranda J, Barbé J. Mutations in the β-Subunit of the RNA Polymerase Impair the Surface-Associated Motility and Virulence of Acinetobacter baumannii. Infect Immun. 2017 Jul 19;85(8). pii: e00327-17. doi: 10.1128/IAI.00327-17. Print 2017 Aug. PubMed PMID: 28507065; PubMed Central PMCID: PMC5520429.
  • Otero F, Gosálvez J, Bou G, Fernández JL. Simple and Fast Detection of Resistance to Antibiotic Inhibitors of Protein Synthesis in Gram-Negative Pathogens Through Evaluation of Mitomycin C-Induced Cell Elongation. Microb Drug Resist. 2017 Dec;23(8):973-981. doi: 10.1089/mdr.2017.0028. Epub 2017 May 3. PubMed PMID: 28467172.
  • Sánchez-Encinales V, Álvarez-Marín R, Pachón-Ibáñez ME, Fernández-Cuenca F, Pascual A, Garnacho-Montero J, Martínez-Martínez L, Vila J, Tomás MM, Cisneros JM, Bou G, Rodríguez-Baño J, Pachón J, Smani Y. Overproduction of Outer Membrane Protein A by Acinetobacter baumannii as a Risk Factor for Nosocomial Pneumonia, Bacteremia, and Mortality Rate Increase. J Infect Dis. 2017 Mar 15;215(6):966-974. doi: 10.1093/infdis/jix010. PubMed PMID: 28453834.
  • Oviaño M, Gómara M, Barba MJ, Revillo MJ, Barbeyto LP, Bou G. Towards the early detection of β-lactamase-producing Enterobacteriaceae by MALDI-TOF MS analysis. J Antimicrob Chemother. 2017 Aug 1;72(8):2259-2262. doi: 10.1093/jac/dkx127. PubMed PMID: 28444315.
  • Rumbo-Feal S, Pérez A, Ramelot TA, Álvarez-Fraga L, Vallejo JA, Beceiro A, Ohneck EJ, Arivett BA, Merino M, Fiester SE, Kennedy MA, Actis LA, Bou G, Poza M. Contribution of the A. baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence. Front Cell Infect Microbiol. 2017 Apr 3;7:108. doi: 10.3389/fcimb.2017.00108. eCollection 2017. PubMed PMID: 28421168; PubMed Central PMCID: PMC5376624.
  • López M, Mayer C, Fernández-García L, Blasco L, Muras A, Ruiz FM, Bou G, Otero A, Tomás M; GEIH-GEMARA (SEIMC). Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme. PLoS One. 2017 Mar 22;12(3):e0174454. doi: 10.1371/journal.pone.0174454. eCollection 2017. PubMed PMID: 28328989; PubMed Central PMCID: PMC5362224.
  • Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A. WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones. Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02529-16. doi: 10.1128/AAC.02529-16. Print 2017 Jun. PubMed PMID: 28289035; PubMed Central PMCID: PMC5444176.
  • Oviaño M, Ramírez CL, Barbeyto LP, Bou G. Rapid direct detection of carbapenemase-producing Enterobacteriaceae in clinical urine samples by MALDI-TOF MS analysis. J Antimicrob Chemother. 2017 May 1;72(5):1350-1354. doi: 10.1093/jac/dkw579. PubMed PMID: 28119478.
  • Delgado-Valverde M, Valiente-Mendez A, Torres E, Almirante B, Gómez-Zorrilla S, Borrell N, Aller-García AI, Gurgui M, Almela M, Sanz M, Bou G, Martínez-Martínez L, Cantón R, Antonio Lepe J, Causse M, Gutiérrez-Gutiérrez B, Pascual Á, Rodríguez-Baño J; REIPI/GEIH-SEIMC BACTERAEMIA-MIC Group. MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterobacteriaceae. J Antimicrob Chemother. 2017 May 1;72(5):1478-1487. doi: 10.1093/jac/dkw562. PubMed PMID: 28093484.
  • Oviaño M, Rodríguez-Martínez JM, Pascual Á, Bou G. Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6')-Ib-cr in Enterobacteriaceae by MALDI-TOF MS analysis. J Antimicrob Chemother. 2017 Apr 1;72(4):1074-1080. doi: 10.1093/jac/dkw552. PubMed PMID: 28065892.
  • Palacios-Baena ZR, Gutiérrez-Gutiérrez B, De Cueto M, Viale P, Venditti M, Hernández-Torres A, Oliver A, Martínez-Martínez L, Calbo E, Pintado V, Gasch O, Almirante B, Antonio Lepe J, Pitout J, Akova M, Peña-Miralles C, Schwaber MJ, Tumbarello M, Tacconelli E, Origüen J, Prim N, Bou G, Giamarellou H, Bermejo J, Hamprecht A, Pérez F, Almela M, Lowman W, Hsueh PR, Navarro-San Francisco C, Torre-Cisneros J, Carmeli Y, Bonomo RA, Paterson DL, Pascual Á, Rodríguez-Baño J; REIPI/ESGBIS/INCREMENT Group. Development and validation of the INCREMENT-ESBL predictive score for mortality in patients with bloodstream infections due to extended-spectrum-β-lactamase-producing Enterobacteriaceae. J Antimicrob Chemother. 2017 Mar 1;72(3):906-913. doi: 10.1093/jac/dkw513. PubMed PMID: 28062685.
  • Inmaculada Tomás; et al. 2017. Quantification by qPCR of Pathobionts in Chronic Periodontitis: Development of Predictive Models and Diagnostic Nomograms of Disease Severity (PMID: 28848499) Frontiers in Microbiology.
  • Fernandez-Garcia L; et al. . 2017. Response to bile salts in clinical strains of Acinetobacter baumannii lacking the AdeABC efflux pump: virulence associated with Quorum Sensing (PMID: 28536672) Frontiers in Cellular and Infection Microbiology. dio:10.3389/fcmb.2017.00143.
  • LopezM;etal.2017.Quorumsensingnetworkinclinicalstrainsof A.baumannii: AidA is a new quorum quenching enzyme (PMID: 28328989) PloS One. 12-3.
  • Laura Fernandez-García; et al. 2016. Toxin-Antitoxin Systems in Clinical Pathogens (PMID: 27447671) Toxins. Building.
  • Barbosa BG, Fernandez-García L, Gato E, López M, Blasco L, Leão RS, Albano RM, Fernández B, Cuenca FF, Pascual Á, Bou G, Marques EA, Tomás M. Genome Sequence of Airborne Acinetobacter sp. Strain 5-2Ac02 in the Hospital Environment, Close to the Species of Acinetobacter towneri. Genome Announc. 2016 Dec 8;4(6). pii: e01343-16. doi: 10.1128/genomeA.01343-16. PubMed PMID: 27932646; PubMed Central PMCID: PMC5146438.
  • Soares NC, Bou G, Blackburn JM. Editorial: Proteomics of Microbial Human Pathogens. Front Microbiol. 2016 Nov 4;7:1742. eCollection 2016. PubMed PMID: 27867374; PubMed Central PMCID: PMC5095502.
  • Oviaño M, Bou G. Imipenem-avibactam: a novel combination for the rapid detection of carbapenemase activity in Enterobacteriaceae and Acinetobacter baumannii by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Diagn Microbiol Infect Dis. 2017 Feb;87(2):129-132. doi: 10.1016/j.diagmicrobio.2016.10.016. Epub 2016 Oct 18. PubMed PMID: 27863949.
  • Oviaño M, Sparbier K, Barba MJ, Kostrzewa M, Bou G. Universal protocol for the rapid automated detection of carbapenem-resistant Gram-negative bacilli directly from blood cultures by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF/MS). Int J Antimicrob Agents. 2016 Dec;48(6):655-660. doi: 10.1016/j.ijantimicag.2016.08.024. Epub 2016 Oct 20. PubMed PMID: 27836381.
  • Cantón R, Livermore DM, Morosini MI, Díaz-Regañón J, Rossolini GM; PREMIUM Study Group. Etest® versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: results from PREMIUM, a European multicentre study. J Antimicrob Chemother. 2017 Feb;72(2):431-436. doi: 10.1093/jac/dkw442. Epub 2016 Oct 20. PubMed PMID: 27798220.
  • Garnacho-Montero J, Gutiérrez-Pizarraya A, Díaz-Martín A, Cisneros-Herreros JM, Cano ME, Gato E, Ruiz de Alegría C, Fernández-Cuenca F, Vila J, Martínez-Martínez L, Tomás-Carmona MD, Pascual Á, Bou G, Pachón-Diaz J, Rodríguez-Baño J. Acinetobacter baumannii in critically ill patients: Molecular epidemiology, clinical features and predictors of mortality. Enferm Infecc Microbiol Clin. 2016 Nov;34(9):551-558. doi: 10.1016/j.eimc.2015.11.018. Epub 2016 Jan 25. PubMed PMID: 26821549.
  • Oviaño M, Torres I, González M, Bou G. Evaluation of a novel procedure for rapid detection of carbapenemase-producing Enterobacteriaceae (CPE) using the LightMix® modular carbapenemase kits. J Antimicrob Chemother. 2016 Dec;71(12):3420-3423. Epub 2016 Aug 26. PubMed PMID: 27566313; PubMed Central PMCID: PMC5400078.
  • Fernández-García L, Blasco L, Lopez M, Bou G, García-Contreras R, Wood T, Tomas M. Toxin-Antitoxin Systems in Clinical Pathogens. Toxins (Basel). 2016 Jul 20;8(7). pii: E227. doi: 10.3390/toxins8070227. Review. PubMed PMID: 27447671; PubMed Central PMCID: PMC4963858.
  • Oviaño M, Dolores Rojo M, Navarro Marí JM, Bou G. [Rapid detection of antimicrobial resistance by MALDI-TOF mass spectrometry]. Enferm Infecc Microbiol Clin. 2016 Jun;34 Suppl 2:36-41. doi: 10.1016/S0213-005X(16)30189-6. Review. Spanish. PubMed PMID: 27389291.
  • Otero F, Tamayo M, Santiso R, Gosálvez J, Bou G, Fernández JL. Rapid Assessment of Resistance to Antibiotic Inhibitors of Protein Synthesis in the Gram-Positive Pathogens, Enterococcus faecalis and Streptococcus pneumoniae, Based on Evaluation of the Lytic Response. Microb Drug Resist. 2017 Apr;23(3):267-271. doi: 10.1089/mdr.2016.0091. Epub 2016 Jul 6. PubMed PMID: 27383851.
  • Machuca J, Agüero J, Miró E, Conejo MDC, Oteo J, Bou G, González-López JJ, Oliver A, Navarro F, Pascual Á, Martínez-Martínez L. Prevalence of quinolone resistance mechanisms in Enterobacteriaceae producing acquired AmpC β-lactamases and/or carbapenemases in Spain. Enferm Infecc Microbiol Clin. 2017 Oct;35(8):487-492. doi: 10.1016/j.eimc.2016.05.006. Epub 2016 Jun 23. English, Spanish. PubMed PMID: 27345951.
  • Otero F, Santiso R, Tamayo M, Fernández JL, Bou G, Lepe JA, McConnell MJ, Gosálvez J, Cisneros JM. Rapid Detection of Antibiotic Resistance in Gram-Negative Bacteria Through Assessment of Changes in Cellular Morphology. Microb Drug Resist. 2017 Mar;23(2):157-162. doi: 10.1089/mdr.2016.0023. Epub 2016 Jun 3. PubMed PMID: 27259183.
  • Gutiérrez-Gutiérrez B, Pérez-Galera S, Salamanca E, de Cueto M, Calbo E, Almirante B, Viale P, Oliver A, Pintado V, Gasch O, Martínez-Martínez L, Pitout J, Akova M, Peña C, Molina J, Hernández A, Venditti M, Prim N, Origüen J, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Giamarellou H, Almela M, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Mora-Rillo M, Natera C, Souli M, Bonomo RA, Carmeli Y, Paterson DL, Pascual A, Rodríguez-Baño J. A Multinational, Preregistered Cohort Study of β-Lactam/β-Lactamase Inhibitor Combinations for Treatment of Bloodstream Infections Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4159-69. doi: 10.1128/AAC.00365-16. Print 2016 Jul. PubMed PMID: 27139473; PubMed Central PMCID: PMC4914653.
  • Martínez-Guitián M, Vázquez-Ucha JC, Odingo J, Parish T, Poza M, Waite RD, Bou G, Wareham DW, Beceiro A. Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4375-9. doi: 10.1128/AAC.00510-16. Print 2016 Jul. PubMed PMID: 27139471; PubMed Central PMCID: PMC4914650.
  • Vallejo JA, Martínez-Guitián M, Vázquez-Ucha JC, González-Bello C, Poza M, Buynak JD, Bethel CR, Bonomo RA, Bou G, Beceiro A. LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48. J Antimicrob Chemother. 2016 Aug;71(8):2171-80. doi: 10.1093/jac/dkw105. Epub 2016 Apr 28. PubMed PMID: 27125555; PubMed Central PMCID: PMC4954921.
  • Pérez-Llarena FJ, Bou G. Proteomics As a Tool for Studying Bacterial Virulence and Antimicrobial Resistance. Front Microbiol. 2016 Mar 31;7:410. doi: 10.3389/fmicb.2016.00410. eCollection 2016. Review. PubMed PMID: 27065974; PubMed Central PMCID: PMC4814472.
  • Prado V, Lence E, Maneiro M, Vázquez-Ucha JC, Beceiro A, Thompson P, Hawkins AR, González-Bello C. Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme. J Med Chem. 2016 Jun 9;59(11):5471-87. doi: 10.1021/acs.jmedchem.6b00483. Epub 2016 May 18. PubMed PMID: 27191386.
  • Gutiérrez-Gutiérrez B, Bonomo RA, Carmeli Y, Paterson DL, Almirante B, Martínez-Martínez L, Oliver A, Calbo E, Peña C, Akova M, Pitout J, Origüen J, Pintado V, García-Vázquez E, Gasch O, Hamprecht A, Prim N, Tumbarello M, Bou G, Viale P, Tacconelli E, Almela M, Pérez F, Giamarellou H, Cisneros JM, Schwaber MJ, Venditti M, Lowman W, Bermejo J, Hsueh PR, Mora-Rillo M, Gracia-Ahulfinger I, Pascual A, Rodríguez-Baño J; REIPI/ESGBIS/INCREMENT Group. Ertapenem for the treatment of bloodstream infections due to ESBL-producing Enterobacteriaceae: a multinational pre-registered cohort study. J Antimicrob Chemother. 2016 Jun;71(6):1672-80. doi: 10.1093/jac/dkv502. Epub 2016 Feb 22. PubMed PMID: 26907184; PubMed Central PMCID: PMC4867097.
  • Rodríguez-Martínez JM, Santiso R, Machuca J, Bou G, Pascual Á, Fernández JL. Assessment of Chromosomal DNA Fragmentation by Quinolones in an Isogenic Collection of Escherichia coli with Defined Resistance Mechanisms. Microb Drug Resist. 2016 Jul;22(5):354-9. doi: 10.1089/mdr.2015.0298. Epub 2016 Feb 18. PubMed PMID: 26890225.
  • Prado V, Lence E, Vallejo JA, Beceiro A, Thompson P, Hawkins AR, González-Bello C. Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy. Chemistry. 2016 Feb 18;22(8):2758-68. doi: 10.1002/chem.201504438. Epub 2016 Jan 21. PubMed PMID: 26797764
  • González-Bello C, Tizón L, Lence E, Otero JM, van Raaij MJ, Martinez-Guitian M, Beceiro A, Thompson P, Hawkins AR. Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct. J Am Chem Soc. 2015 Jul 29;137(29):9333-43. doi: 10.1021/jacs.5b04080. Epub 2015 Jul 16. PubMed PMID: 26148116
  • Oteo J, Bou G, Chaves F, Oliver A. Microbiological methods for surveillance of carrier status of multiresistant bacteria. Enferm Infecc Microbiol Clin. 2017 Dec;35(10):667-675. doi: 10.1016/j.eimc.2015.12.013. Epub 2016 Feb 8. English, Spanish. PubMed PMID: 26869070.
  • Álvarez-Fraga L, Pérez A, Rumbo-Feal S, Merino M, Vallejo JA, Ohneck EJ, Edelmann RE, Beceiro A, Vázquez-Ucha JC, Valle J, Actis LA, Bou G, Poza M. Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cells. Virulence. 2016 May 18;7(4):443-55. doi: 10.1080/21505594.2016.1145335. Epub 2016 Feb 8. PubMed PMID: 26854744; PubMed Central PMCID: PMC4871663.
  • Catel-Ferreira M, Marti S, Guillon L, Jara L, Coadou G, Molle V, Bouffartigues E, Bou G, Shalk I, Jouenne T, Vila-Farrés X, Dé E. The outer membrane porin OmpW of Acinetobacter baumannii is involved in iron uptake and colistin binding. FEBS Lett. 2016 Jan;590(2):224-31. doi: 10.1002/1873-3468.12050. Epub 2016 Jan 11. PubMed PMID: 26823169.
  • Oviaño M, Barba MJ, Fernández B, Ortega A, Aracil B, Oteo J, Campos J, Bou G. Rapid Detection of OXA-48-Producing Enterobacteriaceae by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. J Clin Microbiol. 2016 Mar;54(3):754-9. doi: 10.1128/JCM.02496-15. Epub 2015 Dec 16. PubMed PMID: 26677247; PubMed Central PMCID: PMC4767963.
  • Moure R, Cañizares Á, Muíño M, Lobato M, Fernández A, Rodríguez M, Gude MJ, Tomás M, Bou G. Use of the cobas 4800 system for the rapid detection of toxigenic Clostridium difficile and methicillin-resistant Staphylococcus aureus. J Microbiol Methods. 2016 Jan;120:50-2. doi: 10.1016/j.mimet.2015.11.014. Epub 2015 Nov 29. PubMed PMID: 26611812.
  • Palacios-Baena ZR, Oteo J, Conejo C, Larrosa MN, Bou G, Fernández-Martínez M, González-López JJ, Pintado V, Martínez-Martínez L, Merino M, Pomar V, Mora-Rillo M, Rivera MA, Oliver A, Ruiz-Carrascoso G, Ruiz-Garbajosa P, Zamorano L, Bautista V, Ortega A, Morales I, Pascual Á, Campos J, Rodríguez-Baño J; GEIH-GEMARA (SEIMC) and REIPI Group for CPE. Comprehensive clinical and epidemiological assessment of colonisation and infection due to carbapenemase-producing Enterobacteriaceae in Spain. J Infect. 2016 Feb;72(2):152-60. doi: 10.1016/j.jinf.2015.10.008. Epub 2015 Nov 4. PubMed PMID: 26546855.
  • Fernández-Cuenca F, Tomás M, Caballero-Moyano FJ, Bou G, Martínez-Martínez L, Vila J, Pachón J, Cisneros JM, Rodríguez-Baño J, Pascual Á; Spanish Group of Nosocomial Infections (GEIH) from the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC) and the Spanish Network for Research in Infectious Diseases (REIPI); Spanish Group of Nosocomial Infections GEIH from the Spanish Society of Clinical Microbiology and Infectious Diseases SEIMC and the Spanish Network for Research in Infectious Diseases REIPI. Reduced susceptibility to biocides in Acinetobacter baumannii: association with resistance to antimicrobials, epidemiological behaviour, biological cost and effect on the expression of genes encoding porins and efflux pumps. J Antimicrob Chemother. 2015 Dec;70(12):3222-9. doi: 10.1093/jac/dkv262. Epub 2015 Sep 10. PubMed PMID: 26517560.
  • Jara LM, Pérez-Varela M, Corral J, Arch M, Cortés P, Bou G, Aranda J, Barbé J. Novobiocin Inhibits the Antimicrobial Resistance Acquired through DNA Damage-Induced Mutagenesis in Acinetobacter baumannii. Antimicrob Agents Chemother. 2015 Oct 26;60(1):637-9. doi: 10.1128/AAC.01810-15. Print 2016 Jan. PubMed PMID: 26503651; PubMed Central PMCID: PMC4704144.
  • Álvarez-Fraga L, López M, Merino M, Rumbo-Feal S, Tomás M, Bou G, Poza M. Draft Genome Sequence of the Biofilm-Hyperproducing Acinetobacter baumannii Clinical Strain MAR002. Genome Announc. 2015 Jul 23;3(4). pii: e00824-15. doi: 10.1128/genomeA.00824-15. PubMed PMID: 26205868; PubMed Central PMCID: PMC4513162.
  • Oteo J, Alcaraz R, Bou G, Conejo C, Díaz-Lamas AM, Fernández-Martínez M, Fontanals D, González-López JJ, López-Contreras J, Martínez-Martínez L, Mora-Rillo M, Muñoz M, Navarro F, Oliver A, Pintado V, Ruiz-Carrascoso G, Ruiz-Garbajosa P, Sánchez-Porto A, Sánchez-Romero I, Zamorano L, Aracil B, Rodríguez-Baño J; Spanish Network for Research in Infectious Diseases (REIPI); GEIH-GEMARA (SEIMC). Rates of faecal colonization by carbapenemase-producing Enterobacteriaceae among patients admitted to ICUs in Spain. J Antimicrob Chemother. 2015 Oct;70(10):2916-8. doi: 10.1093/jac/dkv187. Epub 2015 Jul 9. PubMed PMID: 26163400.
  • Méndez JA, Mateos J, Beceiro A, Lopez M, Tomás M, Poza M, Bou G. Quantitative proteomic analysis of host--pathogen interactions: a study of Acinetobacter baumannii responses to host airways. BMC Genomics. 2015 May 30;16:422. doi: 10.1186/s12864-015-1608-z. PubMed PMID: 26025090; PubMed Central PMCID: PMC4449591.
  • Fernández-Martínez M, Miró E, Ortega A, Bou G, González-López JJ, Oliver A, Pascual A, Cercenado E, Oteo J, Martínez-Martínez L, Navarro F; Spanish Network for the Research in Infectious Diseases (REIPI). Molecular identification of aminoglycoside-modifying enzymes in clinical isolates of Escherichia coli resistant to amoxicillin/clavulanic acid isolated in Spain. Int J Antimicrob Agents. 2015 Aug;46(2):157-63. doi: 10.1016/j.ijantimicag.2015.03.008. Epub 2015 Apr 29. PubMed PMID: 26022930.
  • Jara LM, Cortés P, Bou G, Barbé J, Aranda J. Differential roles of antimicrobials in the acquisition of drug resistance through activation of the SOS response in Acinetobacter baumannii. Antimicrob Agents Chemother. 2015 Jul;59(7):4318-20. doi: 10.1128/AAC.04918-14. Epub 2015 Apr 20. PubMed PMID: 25896685; PubMed Central PMCID: PMC4468734.
  • Oteo J, Ortega A, Bartolomé R, Bou G, Conejo C, Fernández-Martínez M, González-López JJ, Martínez-García L, Martínez-Martínez L, Merino M, Miró E, Mora M, Navarro F, Oliver A, Pascual Á, Rodríguez-Baño J, Ruiz-Carrascoso G, Ruiz-Garbajosa P, Zamorano L, Bautista V, Pérez-Vázquez M, Campos J; GEIH-GEMARA (SEIMC) and REIPI. Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem. Antimicrob Agents Chemother. 2015;59(6):3406-12. doi: 10.1128/AAC.00086-15. Epub 2015 Mar 30. PubMed PMID: 25824224; PubMed Central PMCID: PMC4432182.
  • Rodríguez-Beltrán J, Cabot G, Valencia EY, Costas C, Bou G, Oliver A, Blázquez J. N-acetylcysteine selectively antagonizes the activity of imipenem in Pseudomonas aeruginosa by an OprD-mediated mechanism. Antimicrob Agents Chemother. 2015;59(6):3246-51. doi: 10.1128/AAC.00017-15. Epub 2015 Mar 23. PubMed PMID: 25801561; PubMed Central PMCID: PMC4432192.
  • Rodríguez-Baño J, Cisneros JM, Cobos-Trigueros N, Fresco G, Navarro-San Francisco C, Gudiol C, Horcajada JP, López-Cerero L, Martínez JA, Molina J, Montero M, Paño-Pardo JR, Pascual A, Peña C, Pintado V, Retamar P, Tomás M, Borges-Sa M, Garnacho-Montero J, Bou G; Study Group of Nosocomial Infections (GEIH) of the Spanish Society of Infectious Diseases, Infectious Diseases (SEIMC). Diagnosis and antimicrobial treatment of invasive infections due to multidrug-resistant Enterobacteriaceae. Guidelines of the Spanish Society of Infectious Diseases and Clinical Microbiology. Enferm Infecc Microbiol Clin. 2015 May;33(5):337.e1-337.e21. doi: 10.1016/j.eimc.2014.11.009. Epub 2015 Jan 15. PubMed PMID: 25600218.
  • Rodríguez-Baño J, Cisneros JM, Cobos-Trigueros N, Fresco G, Navarro-San Francisco C, Gudiol C, Horcajada JP, López-Cerero L, Martínez JA, Molina J, Montero M, Paño-Pardo JR, Pascual A, Peña C, Pintado V, Retamar P, Tomás M, Borges-Sa M, Garnacho-Montero J, Bou G; Study Group of Nosocomial Infections (GEIH) of the Spanish Society of Infectious Diseases, Infectious Diseases (SEIMC). Executive summary of the diagnosis and antimicrobial treatment of invasive infections due to multidrug-resistant Enterobacteriaceae. Guidelines of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC). Enferm Infecc Microbiol Clin. 2015 May;33(5):338-41. doi: 10.1016/j.eimc.2014.11.015. Epub 2015 Jan 4. PubMed PMID: 25563393.
  • Bou G, Vila J, Seral C, Castillo FJ. Detection of carbapenemase-producing Enterobacteriaceae in various scenarios and health settings. Enferm Infecc Microbiol Clin. 2014 Dec;32 Suppl 4:24-32. doi: 10.1016/S0213-005X(14)70171-5. PubMed PMID: 25542049.
  • Mena A, Moldes L, Meijide H, Cañizares A, Castro-Iglesias A, Delgado M, Pértega S, Pedreira J, Bou G, Poveda E. Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing. PLoS One. 2014 Dec 1;9(12):e113062. doi: 10.1371/journal.pone.0113062. eCollection 2014. PubMed PMID: 25436642; PubMed Central PMCID: PMC4249795.
  • Villar M, Cano ME, Gato E, Garnacho-Montero J, Miguel Cisneros J, Ruíz de Alegría C, Fernández-Cuenca F, Martínez-Martínez L, Vila J, Pascual A, Tomás M, Bou G, Rodríguez-Baño J; GEIH/GEMARA/REIPI-Ab20101 Group. Epidemiologic and clinical impact of Acinetobacter baumannii colonization and infection: a reappraisal. Medicine (Baltimore). 2014 Jul;93(5):202-10. doi: 10.1097/MD.0000000000000036. PubMed PMID: 25181313; PubMed Central PMCID: PMC4602455.
  • Rumbo C, Tomás M, Fernández Moreira E, Soares NC, Carvajal M, Santillana E, Beceiro A, Romero A, Bou G. The Acinetobacter baumannii Omp33-36 porin is a virulence factor that induces apoptosis and modulates autophagy in human cells. Infect Immun. 2014 Nov;82(11):4666-80. doi: 10.1128/IAI.02034-14. Epub 2014 Aug 25. PubMed PMID: 25156738; PubMed Central PMCID: PMC4249306.
  • Pérez-Llarena FJ, Zamorano L, Kerff F, Beceiro A, García P, Miró E, Larrosa N, Gómez-Bertomeu F, Méndez JA, González-López JJ, Oliver A, Galleni M, Navarro F, Bou G. Genetic and kinetic characterization of the novel AmpC β-lactamases DHA-6 and DHA-7. Antimicrob Agents Chemother. 2014 Nov;58(11):6544-9. doi: 10.1128/AAC.03144-14. Epub 2014 Aug 18. PubMed PMID: 25136023; PubMed Central PMCID: PMC4249421.
  • Cayô R, Merino M, Ruiz Del Castillo B, Cano ME, Calvo J, Bou G, Martínez-Martínez L. OXA-207, a novel OXA-24 variant with reduced catalytic efficiency against carbapenems in Acinetobacter pittii from Spain. Antimicrob Agents Chemother. 2014 Aug;58(8):4944-8. doi: 10.1128/AAC.02633-13. Epub 2014 Jun 2. PubMed PMID: 24890588; PubMed Central PMCID: PMC4136014.
  • Mosqueda N, Gato E, Roca I, López M, de Alegría CR, Fernández Cuenca F, Martínez-Martínez L, Pachón J, Cisneros JM, Rodríguez-Baño J, Pascual A, Vila J, Bou G, Tomás M; GEIH-GEMARA (SEIMC) and REIPI. Characterization of plasmids carrying the blaOXA-24/40 carbapenemase gene and the genes encoding the AbkA/AbkB proteins of a toxin/antitoxin system. J Antimicrob Chemother. 2014 Oct;69(10):2629-33. doi: 10.1093/jac/dku179. Epub 2014 May 30. PubMed PMID: 24879663.
  • Pérez A, Pérez-Llarena FJ, García P, Kerff F, Beceiro A, Galleni M, Bou G. New mutations in ADC-type β-lactamases from Acinetobacter spp. affect cefoxitin and ceftazidime hydrolysis. J Antimicrob Chemother. 2014 Sep;69(9):2407-11. doi: 10.1093/jac/dku163. Epub 2014 May 20. PubMed PMID: 24845871.
  • Oteo J, González-López JJ, Ortega A, Quintero-Zárate JN, Bou G, Cercenado E, Conejo MC, Martínez-Martínez L, Navarro F, Oliver A, Bartolomé RM, Campos J; Spanish Network for Research in Infectious Diseases (REIPI). Inhibitor-resistant TEM- and OXA-1-producing Escherichia coli isolates resistant to amoxicillin-clavulanate are more clonal and possess lower virulence gene content than susceptible clinical isolates. Antimicrob Agents Chemother. 2014 Jul;58(7):3874-81. doi: 10.1128/AAC.02738-13. Epub 2014 Apr 28. PubMed PMID: 24777096; PubMed Central PMCID: PMC4068566.
  • Oteo J, Calbo E, Rodríguez-Baño J, Oliver A, Hornero A, Ruiz-Garbajosa P, Horcajada JP, Del Pozo JL, Riera M, Sierra R, Bou G, Salavert M. [The threat of the carbapenemase-producing enterobacteriaceae in Spain: positioning report of the SEIMC study groups, GEIH and GEMARA]. Enferm Infecc Microbiol Clin. 2014 Dec;32(10):666-70. doi: 10.1016/j.eimc.2014.02.011. Epub 2014 Apr 22. Spanish. PubMed PMID: 24767691.
  • Soares NC, Spät P, Méndez JA, Nakedi K, Aranda J, Bou G. Ser/Thr/Tyr phosphoproteome characterization of Acinetobacter baumannii: comparison between a reference strain and a highly invasive multidrug-resistant clinical isolate. J Proteomics. 2014 May 6;102:113-24. doi: 10.1016/j.jprot.2014.03.009. Epub 2014 Mar 21. PubMed PMID: 24657496.
  • Bou G. [Relationship between resistance and virulence in bacteria of clinical interest]. Enferm Infecc Microbiol Clin. 2014 Jan;32(1):1-3. doi: 10.1016/j.eimc.2013.11.002. Epub 2013 Dec 20. Spanish. PubMed PMID: 24360834.
  • Aranda J, López M, Leiva E, Magán A, Adler B, Bou G, Barbé J. Role of Acinetobacter baumannii UmuD homologs in antibiotic resistance acquired through DNA damage-induced mutagenesis. Antimicrob Agents Chemother. 2014;58(3):1771-3. doi: 10.1128/AAC.02346-13. Epub 2013 Dec 16. PubMed PMID: 24342640; PubMed Central PMCID: PMC3957856.
  • Merino M, Poza M, Roca I, Barba MJ, Sousa MD, Vila J, Bou G. Nosocomial outbreak of a multiresistant Acinetobacter baumannii expressing OXA-23 carbapenemase in Spain. Microb Drug Resist. 2014 Aug;20(4):259-63. doi: 10.1089/mdr.2013.0127. Epub 2013 Dec 11. PubMed PMID: 24328852.
  • Gayoso CM, Mateos J, Méndez JA, Fernández-Puente P, Rumbo C, Tomás M, Martínez de Ilarduya O, Bou G. Molecular mechanisms involved in the response to desiccation stress and persistence in Acinetobacter baumannii. J Proteome Res. 2014 Feb 7;13(2):460-76. doi: 10.1021/pr400603f. Epub 2013 Dec 17. PubMed PMID: 24299215.
  • Papp-Wallace KM, Mallo S, Bethel CR, Taracila MA, Hujer AM, Fernández A, Gatta JA, Smith KM, Xu Y, Page MG, Desarbre E, Bou G, Bonomo RA. A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenems. J Antimicrob Chemother. 2014 Mar;69(3):682-90. doi: 10.1093/jac/dkt434. Epub 2013 Nov 13. PubMed PMID: 24235094; PubMed Central PMCID: PMC3922156.
  • Beceiro A, Moreno A, Fernández N, Vallejo JA, Aranda J, Adler B, Harper M, Boyce JD, Bou G. Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii. Antimicrob Agents Chemother. 2014;58(1):518-26. doi: 10.1128/AAC.01597-13. Epub 2013 Nov 4. PubMed PMID: 24189257; PubMed Central PMCID: PMC3910726.
  • Rumbo, C.; et al.. 2014. The Acinetobacter baumannii Omp33-36 porin is a virulence factor that induces apoptosis and modulates autophagy in human cells (PMID: 25156738) Infection and Immunity. ASM. 82-11, pp.4666-4680. ISSN 0019-9567. N Mosqueda; et al. . 2014. Chraracterization of plasmids carrying the blaOXA-24/40 carbapenemase gene and the genes encoding the AbkA/AbkB proteins of a toxin/antitoxin system (PMID: 24879663) Journal of Antimicrobial and Chemotherapy. Oxford University. 69-10, pp.2629-2633. ISSN 0305
  • Grau S, Bou G, Fondevilla E, Nicolás J, Rodríguez-Maresca M, Martínez-Martínez L. How to measure and monitor antimicrobial consumption and resistance. Enferm Infecc Microbiol Clin. 2013 Sep;31 Suppl 4:16-24. doi: 10.1016/S0213-005X(13)70128-9. PubMed PMID: 24129285.
  • Aranda J, Poza M, Shingu-Vázquez M, Cortés P, Boyce JD, Adler B, Barbé J, Bou G. Identification of a DNA-damage-inducible regulon in Acinetobacter baumannii. J Bacteriol. 2013 Dec;195(24):5577-82. doi: 10.1128/JB.00853-13. Epub 2013 Oct 11. PubMed PMID: 24123815; PubMed Central PMCID: PMC3889614.
  • Rumbo-Feal S, Gómez MJ, Gayoso C, Álvarez-Fraga L, Cabral MP, Aransay AM, Rodríguez-Ezpeleta N, Fullaondo A, Valle J, Tomás M, Bou G, Poza M. Whole transcriptome analysis of Acinetobacter baumannii assessed by RNA-sequencing reveals different mRNA expression profiles in biofilm compared to planktonic cells. PLoS One. 2013 Aug 30;8(8):e72968. doi: 10.1371/journal.pone.0072968. eCollection 2013. PubMed PMID: 24023660; PubMed Central PMCID: PMC3758355.
  • Tamayo M, Santiso R, Otero F, Bou G, Lepe JA, McConnell MJ, Cisneros JM, Gosálvez J, Fernández JL. Rapid determination of colistin resistance in clinical strains of Acinetobacter baumannii by use of the micromax assay. J Clin Microbiol. 2013 Nov;51(11):3675-82. doi: 10.1128/JCM.01787-13. Epub 2013 Aug 28. PubMed PMID: 23985913; PubMed Central PMCID: PMC3889750.
  • Pérez-Llarena FJ, Kerff F, Zamorano L, Fernández MC, Nuñez ML, Miró E, Oliver A, Navarro F, Bou G. Characterization of the new AmpC β-lactamase FOX-8 reveals a single mutation, Phe313Leu, located in the R2 loop that affects ceftazidime hydrolysis. Antimicrob Agents Chemother. 2013 Oct;57(10):5158-61. doi: 10.1128/AAC.00818-13. Epub 2013 Jul 22. PubMed PMID: 23877692; PubMed Central PMCID: PMC3811397.
  • Manso CF, Torres E, Bou G, Romalde JL. Role of norovirus in acute gastroenteritis in the Northwest of Spain during 2010-2011. J Med Virol. 2013 Nov;85(11):2009-15. doi: 10.1002/jmv.23680. Epub 2013 Jul 12. PubMed PMID: 23852802.
  • Rodríguez-Baño J, Oteo J, Ortega A, Villar M, Conejo MC, Bou G, Aranzamendi-Zaldumbide M, Cercenado E, Gurguí M, Martínez-Martínez L, Merino M, Rivera A, Oliver A, Weber I, Pascual A, Bartolomé RM, Gónzalez-López JJ, Campos J. Epidemiological and clinical complexity of amoxicillin-clavulanate-resistant Escherichia coli. J Clin Microbiol. 2013 Jul;51(7):2414-7. doi: 10.1128/JCM.00999-13. Epub 2013 May 1. PubMed PMID: 23637303; PubMed Central PMCID: PMC3697715.
  • Sousa D, Castelo-Corral L, Gutiérrez-Urbón JM, Molina F, López-Calviño B, Bou G, Llinares P. Impact of ertapenem use on Pseudomonas aeruginosa and Acinetobacter baumannii imipenem susceptibility rates: collateral damage or positive effect on hospital ecology? J Antimicrob Chemother. 2013 Aug;68(8):1917-25. doi: 10.1093/jac/dkt091. Epub 2013 Apr 4. PubMed PMID: 23557925.
  • Beceiro A, Tomás M, Bou G. Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world? Clin Microbiol Rev. 2013 Apr;26(2):185-230. doi: 10.1128/CMR.00059-12. Review. PubMed PMID: 23554414; PubMed Central PMCID: PMC3623377.
  • Higgins PG, Pérez-Llarena FJ, Zander E, Fernández A, Bou G, Seifert H. OXA-235, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob Agents Chemother. 2013 May;57(5):2121-6. doi: 10.1128/AAC.02413-12. Epub 2013 Feb 25. PubMed PMID: 23439638; PubMed Central PMCID: PMC3632948.
  • Torres-Sangiao E, Lissarrague-Sanz A, Cañizares-Castellanos A, Bou G. [Bacterial prostatitis]. Enferm Infecc Microbiol Clin. 2013 May;31(5):344-6. doi: 10.1016/j.eimc.2012.09.020. Epub 2012 Dec 23. Spanish. PubMed PMID: 23265934.
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